WEKO3
アイテム
{"_buckets": {"deposit": "d579a03b-56ad-4c81-875b-ca636adae1b8"}, "_deposit": {"created_by": 15, "id": "2525", "owners": [15], "pid": {"revision_id": 0, "type": "depid", "value": "2525"}, "status": "published"}, "_oai": {"id": "oai:oacis.repo.nii.ac.jp:00002525", "sets": ["354", "357", "653"]}, "author_link": ["2867", "3974", "2869", "2369", "3975", "2868", "3973", "2866", "3976"], "item_3_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "618", "bibliographicPageStart": "609", "bibliographicVolumeNumber": "71", "bibliographic_titles": [{"bibliographic_title": "Journal of Oleo Science"}]}]}, "item_3_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We previously conducted a study using HepG2 cells to compare the effect on the secreted apolipoprotein B-100 and apolipoprotein A-1 ratio (B-100/A-1) corresponding to the ratio of low-density to high-density lipoprotein cholesterol (LDL/HDL) among 13 types of trans-octadecenoic acid (t-18:1) positional isomers.\nThe results revealed that trans-5-18:1 (t5) significantly increased B-100/A-1. In this study, 1% of t5 in the diet, corresponding to 2.08 energy%, was administrated golden Syrian hamsters for 4 weeks to reveal the effects on lipid profiles, including LDL/HDL, by comparing cis-9-octadecenoic acid (OA, oleic acid), trans-9-octadecenoic acid (EA), trans-11-octadecenoic acid (VA), and trans-9,trans-12- octadecadienoic acid (TT). LDL/HDL was not significantly different among the groups. However, the cholesterol concentration of medium very low-density lipoprotein (VLDL) was significantly lower in the TT diet than in the OA and t5 diets.\nThe cholesterol concentration of small VLDL was significantly lower in the TT diet than in the OA, t5, and EA diets. The cholesterol concentration of large LDL was significantly lower in the TT diet than in the t5 and EA diets. However, no significant difference was detected between the TT and OA diets. In contrast, the cholesterol concentration of very small HDL was significantly higher in the TT diet than in the t5 diet.\nThese results would support that lipid metabolism is affected by the structure of TFA in animals.\nHowever, t5-18:1 did not significantly change any lipid profile compared to OA existing in nature, and the previous result from the cell experiment showing that t5 increased B-100/A-1 (LDL/HDL) was not confirmed in this animal experiment.", "subitem_description_type": "Abstract"}]}, "item_3_publisher_32": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "日本油化学会"}]}, "item_3_relation_10": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "35283414", "subitem_relation_type_select": "PMID"}}]}, "item_3_relation_11": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.5650/jos.ess21348", "subitem_relation_type_select": "DOI"}}]}, "item_3_relation_13": {"attribute_name": "情報源", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "Publisher\u0027s Version/PDF (OpenAccess)"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.5650/jos.ess21348", "subitem_relation_type_select": "DOI"}}, {"subitem_relation_name": [{"subitem_relation_name_text": "日本油化学会"}], "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://jocs.jp/", "subitem_relation_type_select": "URI"}}]}, "item_3_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1345-8957", "subitem_source_identifier_type": "ISSN"}]}, "item_3_source_id_9": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA11503337", "subitem_source_identifier_type": "NCID"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nagao, Koji"}], "nameIdentifiers": [{"nameIdentifier": "3973", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueno, Junya"}], "nameIdentifiers": [{"nameIdentifier": "3974", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshinaga, Kazuaki"}], "nameIdentifiers": [{"nameIdentifier": "2866", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagai, Toshiharu"}], "nameIdentifiers": [{"nameIdentifier": "2867", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Mizobe, Hoyo"}], "nameIdentifiers": [{"nameIdentifier": "3975", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yoshida, Akihiko"}], "nameIdentifiers": [{"nameIdentifier": "2868", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Beppu, Fumiaki"}], "nameIdentifiers": [{"nameIdentifier": "2869", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Seiya"}], "nameIdentifiers": [{"nameIdentifier": "3976", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "1000040897906", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/1000040897906"}, {"nameIdentifier": "40897906", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=40897906"}]}, {"creatorNames": [{"creatorName": "Gotoh, Naohiro"}], "nameIdentifiers": [{"nameIdentifier": "2369", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "60323854", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=60323854"}]}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "gel permeation chromatography", "subitem_subject_scheme": "Other"}, {"subitem_subject": "hamster", "subitem_subject_scheme": "Other"}, {"subitem_subject": "serum lipids profile", "subitem_subject_scheme": "Other"}, {"subitem_subject": "trans fatty acid isomer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "trans-5-octadecenoic acid", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers"}]}, "item_type_id": "3", "owner": "15", "path": ["354", "357", "653"], "permalink_uri": "https://oacis.repo.nii.ac.jp/records/2525", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-08-23"}, "publish_date": "2022-08-23", "publish_status": "0", "recid": "2525", "relation": {}, "relation_version_is_last": true, "title": ["Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers"], "weko_shared_id": -1}
Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers
https://oacis.repo.nii.ac.jp/records/2525
https://oacis.repo.nii.ac.jp/records/2525da7e6982-e030-423c-a3da-74da69c219dd
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2022-08-23 | |||||
タイトル | ||||||
タイトル | Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | gel permeation chromatography, hamster, serum lipids profile, trans fatty acid isomer, trans-5-octadecenoic acid | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
著者 |
Nagao, Koji
× Nagao, Koji× Ueno, Junya× Yoshinaga, Kazuaki× Nagai, Toshiharu× Mizobe, Hoyo× Yoshida, Akihiko× Beppu, Fumiaki× Tanaka, Seiya× Gotoh, Naohiro |
|||||
書誌情報 |
Journal of Oleo Science 巻 71, 号 4, p. 609-618, 発行日 2022 |
|||||
抄録 | ||||||
内容記述 | We previously conducted a study using HepG2 cells to compare the effect on the secreted apolipoprotein B-100 and apolipoprotein A-1 ratio (B-100/A-1) corresponding to the ratio of low-density to high-density lipoprotein cholesterol (LDL/HDL) among 13 types of trans-octadecenoic acid (t-18:1) positional isomers. The results revealed that trans-5-18:1 (t5) significantly increased B-100/A-1. In this study, 1% of t5 in the diet, corresponding to 2.08 energy%, was administrated golden Syrian hamsters for 4 weeks to reveal the effects on lipid profiles, including LDL/HDL, by comparing cis-9-octadecenoic acid (OA, oleic acid), trans-9-octadecenoic acid (EA), trans-11-octadecenoic acid (VA), and trans-9,trans-12- octadecadienoic acid (TT). LDL/HDL was not significantly different among the groups. However, the cholesterol concentration of medium very low-density lipoprotein (VLDL) was significantly lower in the TT diet than in the OA and t5 diets. The cholesterol concentration of small VLDL was significantly lower in the TT diet than in the OA, t5, and EA diets. The cholesterol concentration of large LDL was significantly lower in the TT diet than in the t5 and EA diets. However, no significant difference was detected between the TT and OA diets. In contrast, the cholesterol concentration of very small HDL was significantly higher in the TT diet than in the t5 diet. These results would support that lipid metabolism is affected by the structure of TFA in animals. However, t5-18:1 did not significantly change any lipid profile compared to OA existing in nature, and the previous result from the cell experiment showing that t5 increased B-100/A-1 (LDL/HDL) was not confirmed in this animal experiment. |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1345-8957 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11503337 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 35283414 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.5650/jos.ess21348 | |||||
情報源 | ||||||
関連識別子 | https://doi.org/10.5650/jos.ess21348 | |||||
関連名称 | Publisher's Version/PDF (OpenAccess) | |||||
情報源 | ||||||
関連識別子 | https://jocs.jp/ | |||||
関連名称 | 日本油化学会 | |||||
出版者 | ||||||
出版者 | 日本油化学会 |