{"created":"2023-07-25T09:59:14.807761+00:00","id":2525,"links":{},"metadata":{"_buckets":{"deposit":"d579a03b-56ad-4c81-875b-ca636adae1b8"},"_deposit":{"created_by":15,"id":"2525","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"2525"},"status":"published"},"_oai":{"id":"oai:oacis.repo.nii.ac.jp:00002525","sets":["187:189:354","187:191:653","41:357"]},"author_link":["2867","3974","2869","2369","3975","2868","3973","2866","3976"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"618","bibliographicPageStart":"609","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"Journal of Oleo Science"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We previously conducted a study using HepG2 cells to compare the effect on the secreted apolipoprotein B-100 and apolipoprotein A-1 ratio (B-100/A-1) corresponding to the ratio of low-density to high-density lipoprotein cholesterol (LDL/HDL) among 13 types of trans-octadecenoic acid (t-18:1) positional isomers.\nThe results revealed that trans-5-18:1 (t5) significantly increased B-100/A-1. In this study, 1% of t5 in the diet, corresponding to 2.08 energy%, was administrated golden Syrian hamsters for 4 weeks to reveal the effects on lipid profiles, including LDL/HDL, by comparing cis-9-octadecenoic acid (OA, oleic acid), trans-9-octadecenoic acid (EA), trans-11-octadecenoic acid (VA), and trans-9,trans-12- octadecadienoic acid (TT). LDL/HDL was not significantly different among the groups. However, the cholesterol concentration of medium very low-density lipoprotein (VLDL) was significantly lower in the TT diet than in the OA and t5 diets.\nThe cholesterol concentration of small VLDL was significantly lower in the TT diet than in the OA, t5, and EA diets. The cholesterol concentration of large LDL was significantly lower in the TT diet than in the t5 and EA diets. However, no significant difference was detected between the TT and OA diets. In contrast, the cholesterol concentration of very small HDL was significantly higher in the TT diet than in the t5 diet.\nThese results would support that lipid metabolism is affected by the structure of TFA in animals.\nHowever, t5-18:1 did not significantly change any lipid profile compared to OA existing in nature, and the previous result from the cell experiment showing that t5 increased B-100/A-1 (LDL/HDL) was not confirmed in this animal experiment."}]},"item_3_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本油化学会"}]},"item_3_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{}}]},"item_3_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.5650/jos.ess21348","subitem_relation_type_select":"DOI"}}]},"item_3_relation_13":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Publisher's Version/PDF (OpenAccess)"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.5650/jos.ess21348","subitem_relation_type_select":"DOI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"日本油化学会"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://jocs.jp/","subitem_relation_type_select":"URI"}}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1345-8957","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11503337","subitem_source_identifier_type":"NCID"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nagao, Koji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ueno, Junya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshinaga, Kazuaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagai, Toshiharu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mizobe, Hoyo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Akihiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Beppu, Fumiaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Seiya"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Gotoh, Naohiro"}],"nameIdentifiers":[{},{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"gel permeation chromatography","subitem_subject_scheme":"Other"},{"subitem_subject":"hamster","subitem_subject_scheme":"Other"},{"subitem_subject":"serum lipids profile","subitem_subject_scheme":"Other"},{"subitem_subject":"trans fatty acid isomer","subitem_subject_scheme":"Other"},{"subitem_subject":"trans-5-octadecenoic acid","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers"}]},"item_type_id":"3","owner":"15","path":["354","357","653"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-08-23"},"publish_date":"2022-08-23","publish_status":"0","recid":"2525","relation_version_is_last":true,"title":["Comparison of Lipoprotein Cholesterol Levels in Golden Syrian Hamster Administrated trans-Octadecenoic Acid Positional Isomers"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-07-25T10:29:53.431622+00:00"}