@article{oai:oacis.repo.nii.ac.jp:00002230,
 author = {Zhang, Zhiwei and Zhou, Tao and Yang, Taehui and Fukaya, Keisuke and Harunari, Enjuro and Saito, Shun and Yamada, Katsuhisa and Imada, Chiaki and Urabe, Daisuke and Igarashi, Yasuhiro},
 journal = {Journal of Organic Chemistry},
 month = {Aug},
 note = {Three new tetronate-class polyketides, nomimicins B, C, and D, along with nomimicin, hereafter named nomimicin A, were isolat-ed from the culture extract of Actinomadura sp. AKA43 collected from floating particles in the deep-sea water of Sagami Bay,Japan. The structures of nomimicins B, C, and D were elucidated through the interpretation of NMR and MS analytical data, andthe absolute configuration was determined by combination of NOESY/ROESY and ECD analyses. Nomimicins B, C, and Dshowed antimicrobial activity against Gram-positive bacteria, Kocuria rhizophila and Bacillus subtilis, with MIC values in therange of 6.5 to 12.5 μg/mL. Nomimicins B and C also displayed cytotoxicity against P388 murine leukemia cells with IC50 valuesof 33 and 89 μM, respectively.},
 pages = {2194--2202},
 title = {Nomimicins B–D, new tetronate-class polyketides from amarine-derived actinomycete of the genus Actinomadura},
 volume = {17},
 year = {2021}
}