{"created":"2023-07-25T09:58:41.673305+00:00","id":1826,"links":{},"metadata":{"_buckets":{"deposit":"26a35b56-4c65-4961-b568-9a0f8ff17cfa"},"_deposit":{"created_by":15,"id":"1826","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"1826"},"status":"published"},"_oai":{"id":"oai:oacis.repo.nii.ac.jp:00001826","sets":["187:189:299","187:191:238","41:427"]},"author_link":["2749","2750","1548","1744","2753"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"173","bibliographicPageStart":"167","bibliographicVolumeNumber":"76","bibliographic_titles":[{"bibliographic_title":"Fish & Shellfish Immunology"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In this study, we investigated maturation-associated changes in non-specific immune responses of ayu against Flavobacterium psychrophilum. The gonadosomatic index was minimum on 16 June, began to increase on 17 July, and reached the maximum value during August. The highest phagocytic rate (16.3%) was observed on 16 June, which decreased significantly to 5.6% on 26 August. The number of viable bacteria after the serum treatment was highest during August, suggesting that bactericidal activity of the serum decreased along with the sexual maturation. Gene expression levels of interleukin-8, and tumor necrosis factor-α in the spleen did not change significantly during this period, whereas the level of suppressor of cytokine signaling (SOCS)3 was significantly higher on 26 August than that on 16 July (p < 0.05). These results suggest that phagocytic activity of trunk kidney leukocytes and serum bactericidal activity against F. psychrophilum decreased with sexual maturation, and that SOCS3 may be related to the decrease in non-specific immune activity in ayu."}]},"item_3_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_3_relation_10":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{}}]},"item_3_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.fsi.2018.03.005","subitem_relation_type_select":"DOI"}}]},"item_3_relation_13":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Publisher's Version/PDF"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.fsi.2018.03.005","subitem_relation_type_select":"DOI"}}]},"item_3_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(c) 2018 Elsevier Ltd.. This is the author's version of the work. It is posted here for your personal use. Not for redistribution. The definitive Version of Record was published in https://doi.org/10.1016/j.fsi.2018.03.005"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"10504648","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10838941","subitem_source_identifier_type":"NCID"}]},"item_3_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Minami, Shungo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suzuki, Kyuma"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Watanabe, Shun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sano, Motohiko"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kato, Goshi"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-03"}],"displaytype":"detail","filename":"AA10838941-76-167.pdf","filesize":[{"value":"335.9 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"AA10838941-76-167 (Text)","url":"https://oacis.repo.nii.ac.jp/record/1826/files/AA10838941-76-167.pdf"},"version_id":"cf36961d-a050-4bb2-946b-f17fe6f64b33"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-03"}],"displaytype":"detail","filename":"AA10838941-76-167_Fig-tab.pdf","filesize":[{"value":"605.8 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"AA10838941-76-167 (Figures&Table)","url":"https://oacis.repo.nii.ac.jp/record/1826/files/AA10838941-76-167_Fig-tab.pdf"},"version_id":"2a09b289-3120-4232-a8f5-8afefedc2420"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Plecoglossus altivelis","subitem_subject_scheme":"Other"},{"subitem_subject":"Flavobacterium psychrophilum","subitem_subject_scheme":"Other"},{"subitem_subject":"Sexual maturation","subitem_subject_scheme":"Other"},{"subitem_subject":"Non-specific immunity","subitem_subject_scheme":"Other"},{"subitem_subject":"Suppression of cytokine signaling 3","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article"}]},"item_title":"Maturation-associated changes in the non-specific immune response against Flavobacterium psychrophilum in Ayu Plecoglossus altivelis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Maturation-associated changes in the non-specific immune response against Flavobacterium psychrophilum in Ayu Plecoglossus altivelis"}]},"item_type_id":"3","owner":"15","path":["238","299","427"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-10-07"},"publish_date":"2019-10-07","publish_status":"0","recid":"1826","relation_version_is_last":true,"title":["Maturation-associated changes in the non-specific immune response against Flavobacterium psychrophilum in Ayu Plecoglossus altivelis"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2023-07-25T10:42:43.530260+00:00"}