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Purification and Determination of the Chemical Structure of the Tyrosinase Inhibitor Produced by Trichoderma viride Strain H1-7 from a Marine Environment
https://oacis.repo.nii.ac.jp/records/2369
https://oacis.repo.nii.ac.jp/records/23692d6c663f-411c-4202-b3f8-11a0910c89eb
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-04-01 | |||||
タイトル | ||||||
タイトル | Purification and Determination of the Chemical Structure of the Tyrosinase Inhibitor Produced by Trichoderma viride Strain H1-7 from a Marine Environment | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | tyrosinase, tyrosinase inhibitor, Trichoderma viride | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
著者 |
Tsuchiya, Takahiro
× Tsuchiya, Takahiro× Yamada, Katsuhisa× Minoura, Katsuhiko× Miyamoto, Katsuhiro× Usami, Yoshihide× Kobayashi, Takeshi× 佐藤, 奈保子× Imada, Chiaki× Tsujibo, Hiroshi |
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書誌情報 |
Biological and Pharmaceutical Bulletin 巻 31, 号 8, p. 1618-1620, 発行日 2008-08-01 |
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抄録 | ||||||
内容記述 | Tyrosinase is a key enzyme in the synthesis of melanin and is widely distributed in animals, plants, and microorganisms. As excessive melanin production causes not only hyperpigmenting effects on human skin but also melanosis in various foods, an inhibitor of tyrosinase has become of interest lately from a practical point of view. In the present study, we purified the tyrosinase inhibitor produced by Trichoderma viride strain H1-7 from a marine environment. The purified inhibitor showed a single peak on HPLC. The chemical structure of this compound was determined by NMR and mass spectrometry analyses. The structure was the same as homothallin II that has been isolated as an antibiotic from T. koningii and T. harzianum. The inhibitor showed competitive inhibition against mushroom tyrosinase. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0918-6158 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10885497 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1248/bpb.31.1618 | |||||
情報源 | ||||||
関連識別子 | https://doi.org/10.1248/bpb.31.1618 | |||||
関連名称 | Publisher's Version/PDF (OpenAccess) | |||||
情報源 | ||||||
関連識別子 | https://www.pharm.or.jp/ | |||||
関連名称 | 日本薬学会 | |||||
論文ID(NAID) | ||||||
識別子タイプ | NAID | |||||
関連識別子 | 110006839029 | |||||
出版者 | ||||||
出版者 | 日本薬学会 |